- トップ
- 東京大学大学院
- 「基礎薬科学特論?」を含む授業
- 一條秀憲先生の「基礎薬科学特論?」の評価一覧
東京大学大学院
一條秀憲先生の「基礎薬科学特論?」の評価一覧
【東京大学大学院】一條秀憲先生が担当する「基礎薬科学特論?」には、1件の授業評価が寄せられています。授業の充実度は星5.0点、楽単度は星5.0点です。会員登録・ログインをして、在学生による評価とシラバスの内容をもとに、授業の選択・履修登録の参考にしましょう。
Bea さんの授業評価
| 学部 学科 | 薬学系研究科 生命薬学専攻 |
|---|---|
| 担当の先生名 | 一條秀憲先生 |
| 授業種別 | 専門科目 |
| 出席 | ほぼ毎回とる |
| 教科書 | 教科書なし・不要 |
| 授業の雰囲気 | - |
| テスト |
前期/中間：
レポートのみ 後期/期末： レポートのみ 持ち込み： テストなし |
| テストの方式や難易度 | - |
| コメント 授業の内容や学べたこと |
From this class, I got a general understanding of the mechanism and diseases which are related to the cell stress response signals. A lot of factors could be the stress sources for the cell, such as acidification, osmotic pressure, UV light, heat, gravity and so on. Also, there are many pathways for a cell to response to the stressful stimulus, which could help the cell to defend against and recover from the damage. I think the cellular stress responses can be classified into groups like the heat shock response, the unfolded protein response (UPR), the DNA damage response, the response to oxidative stress and so on. The protective responses like unfolded protein response or heat shock response were verified to mediate an increase in chaperone protein activity which enhances the protein folding capacity of the cell, thus counteracting the stress and promoting cell survival. If this recovery is failed, the apoptosis will be activated to eliminate the damaged cells from the organism. Furthermore, these cellular stress responses are tightly linked to a lot of diseases. Such as Amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder which is mainly caused by superoxide dismutase (SOD1) via provoking the ER stress and some other mechanisms. So, if we get a better understanding of the molecular mechanisms of these response, I think we could even control these responses. And further achieve new drug discovery based on the molecular targeted treatment approaches. |
| 授業を 受けた時期 |
- |
| 評価 |
|
(2017/04/13) [2441164]
